How do ideas spread, mutate, and survive? Why do we laugh when others laugh, adopt accents, hum songs that refuse to leave our heads, or suddenly find ourselves saying "actually"? This seminar explores the evolution of information through the lens of theory of memes, also known as memetics—the study of how cultural patterns replicate, vary, and undergo selection. Beginning with genes and the logic of biological evolution, we trace the emergence of memes as cultural replicators transmitted through imitation, communication, and media. Along the way we examine mirror neurons, contagious behaviours, habits, dopamine, earworms and mindworms, the Maluma–Takete effect, memetic complexes such as fashion, ideology, and religion, self-referentiality, the formation of the egoplex, viral phenomena, computer viruses and worms, apps, emojis, memecoins, and other contemporary manifestations of cultural evolution. Combining perspectives from evolutionary theory, psychology, neuroscience, philosophy, linguistics, media studies, and computer science, the seminar invites participants to view culture itself as an evolving ecosystem of replicating patterns which often act and express themselves independently from what our bodies, minds and souls "actually" want.