Butlerian Jihad, Orange-Catholic Bible, Great Convention, Planetary Ecology, Zen-Sunni religion, Mentat, Prescience, Golden Path, Spice ... Actors:
Emperor (House Corrino) - its might based on its ruthless military (Sardaukars)
Landsraad
Combine Honnete Ober Advancer Mercantiles (CHOAM)
The Guild
Fremens (an undefined variable)
Ixians (Mechanists of a sort) and Tleilaxu (Shapers of a sort)